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Why AI-based formulation tools are quietly changing the way we run DOEs
Every seasoned formulator knows the moment: A perfectly executed 18-run response-surface design finishes, the contour plots are beautiful, and the predicted optimum sits … just outside the factor levels you originally chose. The lubricant range was too broad and masked a critical interaction. The disintegrant window missed the narrow zone where hardness and dissolution are simultaneously acceptable. The filler-to-binder ratio that looked reasonable on paper produced tablets

Mike Ruch
Jan 143 min read


Optimizing Tablet Development
In tablet development, quality depends on powder properties like true density, particle size, Tabletability, Compressibility, Compactibility per USP <1062> and Pharmeuropa 5.44. TaBlitz Platform, collaborating with Natoli Scientific integrates data on particle size, density, flowability for precise measurements, visualizing to optimize processes, minimize defects and accelerate development.

Mike Ruch
Jul 10, 20255 min read
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